The Comfurt drug normally takes 20 minutes to take effect - but that is because it only has an application by mouth (Application "O") on the chart. I suppose one could even "hot patch" a running cyberbrain and make it nearly instantaneous, but that sounds somewhat risky (bypassing the brain emulation layer). Wouldn't a narcoalgorithm take place quite a bit more quickly? More like the inhalable ones (Alpha, Grin or Kick) and perhaps take 1 minute or 3 Action Turns to take effect as there's no digestion step necessary.
—"I fear all we have done is to awaken a sleeping giant and fill him with a terrible resolve."- Isoroku Yamamoto