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Question asked so many times, once more answered.
Ultimates want to be the best HUMANS they can be using technology and determination for self-improvement. Their name was chosen by themselves. They are pretty much unified. I won't go into their ideology (khem, khem thinly veiled strawman fascists EDIT: better word is supremacists).
Exhumans want to be the best BEINGS they can be using technology and discarding whatever stops them from attaining their vision of perfection. Sometimes it's morals sometimes it is parts of their own personality. Generally they are very extreme in their approach. Some even discard their consciouss mind (Defilers). They are extremely fractured usually among the ways by which they seek perfection. Their name is a "hold it all" term that was given externally. Usually pretty hostile to transhumanity.
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Ultimates want to perfect the human form. Exhumans find this sentimental attachment to the human form to be naive (well at least the ones who haven't thrown away the concept of "sentimental").
Ultimate want to get the training and gear to be the greatest dragonslayers humanity has ever seen. Exhumans want to be the dragon.
If you took the monsters' point of view, everything they did made perfect sense. The trick was learning to think like a monster.
Nah. Ultimates want to be Trascendent Monks of epic scale, Exhumans are just munchkins that care about nothing but "being on the top". Think Epic Githzyanki true neutral for Ultimates, Pun Pun for Exhumans.